Here are my settings for best performance cpu and disk wise for OpenNebula for Windows 10:
DISK = [
CACHE = "none",
DEV_PREFIX = "vd",
DRIVER = "raw",
IMAGE = "win10_done",
IMAGE_UNAME = "oneadmin",
IO = "native" ]
FEATURES = [
ACPI = "yes",
APIC = "yes",
HYPERV = "yes",
LOCALTIME = "yes",
PAE = "yes" ]
HYPERVISOR = "kvm"
INPUT = [
BUS = "usb",
TYPE = "tablet" ]
OS = [
ARCH = "x86_64",
BOOT = "",
MACHINE = "pc-i440fx-xenial" ]
CPU_MODEL = [
MODEL = "Haswell" ]